Clone:
REA767
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
B cell–activating factor, BAFF, TNFSF13B, BLys

Specifications for CD257 (BAFF) Antibody, anti-mouse, REAfinity™

Overview

Clone REA767 recognizes the mouse CD257 antigen, also known as BAFF. CD257 is a type II transmembrane protein and a member of the tumor necrosis factor (TNF) family, which induce pleiotropic biological responses, including cell growth, differentiation, and death. CD257 plays an important role as costimulator of B cell proliferation and function. Expression of CD257 is found on different cell types including monocytes, dendritic cells, and bone marrow stromal cells.
Additional information: Clone REA767 displays negligible binding to Fc receptors.

Alternative names

B cell–activating factor, BAFF, TNFSF13B, BLys

Detailed product information

Technical specifications

CloneREA767
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD257 (BAFF)
Alternative names of antigenB cell–activating factor, BAFF, TNFSF13B, BLys
Molecular mass of antigen [kDa]34
Distribution of antigendendritic cells, monocytes, stromal cells, bone marrow
Entrez Gene ID24099
RRIDAB_2656708, AB_2656709, AB_2656710, AB_2656707

Resources for CD257 (BAFF) Antibody, anti-mouse, REAfinity™

Certificates

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References for CD257 (BAFF) Antibody, anti-mouse, REAfinity™

Publications

  1. Schneider, P. et al. (1999) BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J. Exp. Med. 189(11): 1747-1756
  2. Jiang, Y. et al. (2001) Polymorphism and chromosomal mapping of the mouse gene for B-cell activating factor belonging to the tumor necrosis factor family (Baff) and association with the autoimmune phenotype. Immunogenetics 53(9): 810-813

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