Clone:
REA1212
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
TNFSF12, APO3L, Dr3l, Dr3lg, TWEAK

Specifications for CD255 (TWEAK) Antibody, anti-mouse, REAfinity™

Overview

Clone REA1212 recognizes the mouse CD255 also known as TWEAK which is a type II transmembrane member of the TNF superfamily with a molecular weight of 27 kDa. It is expressed on a variety of cell types and binds to the TWEAK receptor, Fn14. It functions as an inducer of apoptosis in some cell types, promotes angiogenesis and the proliferation of endothelial cells. Furthermore, it is implicated in the induction of inflammatory cytokines.
Additional information: Clone REA1212 displays negligible binding to Fc receptors.

Alternative names

TNFSF12, APO3L, Dr3l, Dr3lg, TWEAK

Detailed product information

Technical specifications

CloneREA1212
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD255 (TWEAK)
Alternative names of antigenTNFSF12, APO3L, Dr3l, Dr3lg, TWEAK
Molecular mass of antigen [kDa]27
Distribution of antigenT cells, endothelial cells, lymphocytes, monocytes, fibroblasts, thymocytes, brain, heart, lung, ovary, pancreas, skeletal muscle, small intestine, spleen
Entrez Gene ID21944
RRIDAB_2819487, AB_2819486

Resources for CD255 (TWEAK) Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD255 (TWEAK) Antibody, anti-mouse, REAfinity™

Publications

  1. Schneider, P. et al. (1999) TWEAK can induce cell death via endogenous TNF and TNF receptor 1. Eur. J. Immunol. 29(6): 1785-1792
  2. Nakayama, M. et al. (2003) Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies. Biochem. Biophys. Res. Commun. 306(4): 819-825
  3. Lynch, C. N. et al. (1999) TWEAK induces angiogenesis and proliferation of endothelial cells. J. Biol. Chem. 274: 8455-8459

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