Clone:
MTW-1
Type of antibody:
Primary antibodies
Isotype:
rat IgG1κ
Applications:
FC
Alternative names:
TNFSF12, APO3L, Dr3l, Dr3lg, TWEAK

Specifications for CD255 (TWEAK) Antibody, anti-mouse

Overview

The monoclonal antibody MTW-1 reacts with mouse CD255 also known as TWEAK which is a type II transmembrane member of the TNF superfamily with a molecular weight of 27 kDa. It is expressed on a variety of cell types and binds to the TWEAK receptor, Fn14. It functions as an inducer of apoptosis in some cell types, promotes angiogenesis and the proliferation of endothelial cells. Furthermore, it is implicated in the induction of inflammatory cytokines.

Alternative names

TNFSF12, APO3L, Dr3l, Dr3lg, TWEAK

Detailed product information

Technical specifications

CloneMTW-1
Clonalitymonoclonal
Isotyperat IgG1κ
Isotype controlIsotype Control Antibody, rat IgG1
Hostrat
Type of antibodyPrimary antibodies
Speciesmouse
AntigenCD255 (TWEAK)
Alternative names of antigenTNFSF12, APO3L, Dr3l, Dr3lg, TWEAK
Molecular mass of antigen [kDa]27
Distribution of antigenendothelial cells, fibroblasts, monocytes, T cells, thymocytes, brain, heart, lung, ovary, pancreas, skeletal muscle, small intestine, spleen
Entrez Gene ID21944
RRIDAB_2656697, AB_2656698, AB_2656696

Resources for CD255 (TWEAK) Antibody, anti-mouse

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD255 (TWEAK) Antibody, anti-mouse

Publications

  1. Schneider, P. et al. (1999) TWEAK can induce cell death via endogenous TNF and TNF receptor 1. Eur. J. Immunol. 29(6): 1785-1792
  2. Nakayama, M. et al. (2003) Characterization of murine TWEAK and its receptor (Fn14) by monoclonal antibodies. Biochem. Biophys. Res. Commun. 306(4): 819-825
  3. Lynch, C. N. et al. (1999) TWEAK induces angiogenesis and proliferation of endothelial cells. J. Biol. Chem. 274: 8455-8459

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