Clone:
SN1a
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC
Alternative names:
TSPAN7, A15, CCG-B7, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b

Specifications for CD231 (TALLA) Antibody, anti-human

Overview

The monoclonal antibody SN1a reacts with the 150 kDa glycoprotein CD231 also known as T cell–acute lymphoblastic leukemia specific antigen (TALLA), which is a member of the tetraspanin family. CD231 is expressed on T cell–type acute lymphoblastic leukemia (T-ALL) cells, skeletal muscle cells, brain, and spleen. It is reported that TALLA plays a role in integrin-mediated migration and can associate with phosphoinositide 4-kinase.

Alternative names

TSPAN7, A15, CCG-B7, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b

Detailed product information

Technical specifications

CloneSN1a
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD231 (TALLA)
Alternative names of antigenTSPAN7, A15, CCG-B7, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2, TM4SF2b
Molecular mass of antigen [kDa]28
Distribution of antigenendothelial cells, neurons, T cells, leukemia cells, brain
Entrez Gene ID7102
RRIDAB_2656477, AB_2656478, AB_2656476

Resources for CD231 (TALLA) Antibody, anti-human

Certificates

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References for CD231 (TALLA) Antibody, anti-human

Publications

  1. Hara, H. et al. (1987)
    Complete suppression of
    in vivo
    growth of human leukemia cells by specific immunotoxins: nude mouse models.
    Proc. Natl. Acad. Sci. U.S.A. 84: 3390-3394
  2. Seon, B. K. et al. (1983) Monoclonal antibody that defines a unique human T-cell leukemia antigen. Proc. Natl. Acad. Sci. U.S.A. 80: 845-849
  3. Matsuzaki, H. et al. (1987) Molecular nature of a cell membrane antigen specific for human T-cell acute lymphoblastic leukemia. Cancer Res. 47 : 4283-4286
  4. Yauch, R. L. et al. (2000) Specific interactions among transmembrane 4 superfamily (TM4SF) proteins and phosphoinositide 4-kinase. Biochem. J. 351: 629-637
  5. Takagi, S. et al. (1995) Identification of a highly specific surface marker of T-cell acute lymphoblastic leukemia and neuroblastoma as a new member of the transmembrane 4 superfamily. Int. J. Cancer 61(5): 706-715

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