Clone:
REA1222
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC, MC
Alternative names:
FCER2, FcεRII, CD23A, CLEC4J, FCE2, IGEBF

Specifications for CD23 Antibody, anti-human, REAfinity™

Overview

Clone REA1222 recognizes the human CD23 antigen, which is a 45 kDa type II transmembrane glycoprotein that belongs to the immunoglobulin family. It is expressed on most mature B cells, monocytes, follicular dendritic cells, and at low levels on T cells, Langerhans cells, eosinophils, and platelets. CD23 is thought to play a role in the regulation of B cell activation and IgE response. It is up-regulated upon B cell activation. The proteolytic cleavage of membrane CD23 can result in the release of soluble forms of the antigen (sCD23) with a reported biological activity.
Additional information: Clone REA1222 displays negligible binding to Fc receptors.

Alternative names

FCER2, FcεRII, CD23A, CLEC4J, FCE2, IGEBF

Detailed product information

Technical specifications

CloneREA1222
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD23
Alternative names of antigenFCER2, FcεRII, CD23A, CLEC4J, FCE2, IGEBF
Molecular mass of antigen [kDa]36
Distribution of antigenB cells, dendritic cells, endothelial cells, Langerhans cells, macrophages, monocytes, NK cells, platelets, T cells, eosinophils, neutrophils, thymocytes
Entrez Gene ID2208
RRIDAB_2811613, AB_2811606, AB_2811614, AB_2811607, AB_2811615, AB_2811608, AB_2811616, AB_2811609, AB_2811617, AB_2811610, AB_2811604, AB_2811612, AB_2811605, AB_2811611

Resources for CD23 Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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