Clone:
H44
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC
Alternative names:
IL18R1, CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP

Specifications for CD218 (IL-18Rα) Antibody, anti-human

Overview

Clone H44 recognizes the CD218 antigen, which is also known as interleukin-18 receptor α chain (IL-18Rα) receptor, is an heterodimeric receptor complex and composed of the IL-18Rα chain and the IL-1 receptor accessory protein-like (IL-1RacPL) or IL-18Rβ chain. CD218 represents the ligand-binding chain, whereas IL-18Rβ is suggested to assist in the formation of a high affinity complex and mediates intracellular signals. IL-18R is expressed on a variety of cells including macrophages, neutrophils, natural killer (NK) cells, endothelial, and smooth muscle cells and an upregulated expression is observed on naive T cells, T helper cell type 1 (Tʜ1) cells, and B cells, in the presence of IL-12.

Alternative names

IL18R1, CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP

Detailed product information

Technical specifications

CloneH44
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD218 (IL-18Rα)
Alternative names of antigenIL18R1, CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP
Distribution of antigenNK cells, endothelial cells, macrophages, neutrophils
RRIDAB_2656347, AB_2656348, AB_2656349, AB_2656350, AB_2656351, AB_2656352, AB_2656353, AB_2656354, AB_2656345

Resources for CD218 (IL-18Rα) Antibody, anti-human

Certificates

Please follow this
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to search for Certificates of Analysis (CoA) by lot number.

References for CD218 (IL-18Rα) Antibody, anti-human

Publications

  1. Kim, S. H. et al. (2001) Functional reconstitution and regulation of IL-18 activity by the IL-18Rβ chain. J. Immunol. 166: 148-154
  2. Nakamura, S. et al. (2000) Expression and responsiveness of human interleukin-18 receptor (IL-18R) on hematopoietic cell lines. Leukemia 14(6): 1052-1059

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