CD2 MicroBeads were developed for the positive selection or depletion of CD2
+
cells from human PBMCs.

Data and images for CD2 MicroBeads, human

Figures

Figure 1

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PBMCs were labeled with CD2 MicroBeads. For positive selection, the cells were separated over an MS Column in a MiniMACS™ Separator. For depletion, the CD2
+
cells were separated over an LD Column in a MidiMACS™ Separator.

Figure 1

PBMCs were labeled with CD2 MicroBeads. For positive selection, the cells were separated over an MS Column in a MiniMACS™ Separator. For depletion, the CD2
+
cells were separated over an LD Column in a MidiMACS™ Separator.

Specifications for CD2 MicroBeads, human

Overview

CD2 MicroBeads were developed for the positive selection or depletion of CD2
+
cells from human PBMCs.

Detailed product information

Background information

CD2 is expressed on all T cells and most NK cells. The CD2 antigen is a 50 kDa single-chain transmembrane glycoprotein, also known as LFA-2 or receptor for sheep erythrocytes.
CD2 MicroBeads can be used for positive selection or depletion of CD2
+
T and NK cells. They can also be used to deplete CD2
+
cells from tonsils to isolate B cells.
1,2

Columns

For positive selection: MS, LS, XS, or autoMACS
®
Columns. For depletion: LD, D, or autoMACS Columns.

References for CD2 MicroBeads, human

Publications

  1. Drenou et al. (2004) Loss of heterozygosity, a frequent but a non-exclusive mechanism responsible for HLA dysregulation in non-Hodgkin's lymphomas. Br J Haematol 127: 40-49
  2. Larousserie, F. et al. (2006) Differential effects of IL-27 on human B cell subsets. J. Immunol. 176: 5890-5897

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