Clone:
REAL771
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
ANPEP, APN, gp150, LAP1, p150, PEPN

Specifications for CD13 Antibody, anti-human, REAdye_lease™

Overview

Clone REAL771 is an antibody fragment derived from the full CD13 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL771 recognizes the CD13 antigen, a type II transmembrane glycoprotein, which is also known as aminopeptidase N or gp150. CD13 is expressed on granulocytes, myeloid progenitors, endothelial cells, epithelial cells, and subset of granular lymphoid cells. It is also broadly expressed in other tissues such as kidney proximal tubules, intestine, and placenta. CD13 is an enzyme that is used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. It also serves as a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in CD13 appear to be a cause of various types of leukemia or lymphoma.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

ANPEP, APN, gp150, LAP1, p150, PEPN

Detailed product information

Technical specifications

CloneREAL771
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenCD13
Alternative names of antigenANPEP, APN, gp150, LAP1, p150, PEPN
Distribution of antigengranulocytes, endothelial cells, epithelial cells, monocytes, lymphocytes, other, neutrophils, liver
RRIDAB_2857797

Resources for CD13 Antibody, anti-human, REAdye_lease™

Certificates

Please follow this
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to search for Certificates of Analysis (CoA) by lot number.

References for CD13 Antibody, anti-human, REAdye_lease™

Publications

  1. Look, A. T. et al. (1989) Human myeloid plasma membrane glycoprotein CD13 (gp150) is identical to aminopeptidase N. J. Clin. Invest. 83(4): 1299-1307
  2. Favaloro, E. J. et al. (1993) CD13 (GP150; aminopeptidase-N): predominant functional activity in blood is localized to plasma and is not cell-surface associated. Exp. Hematol. 21(13): 1695-1701
  3. Yeager, C. L. et al. (1992) Human aminopeptidase N is a receptor for human coronavirus 229E. Nature 357(6377): 420-422

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