Clone:
REA328
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7

Specifications for CCL7 (MCP-3) Antibody, anti-human, REAfinity™

Overview

Clone REA328 recognizes the human C-C motif chemokine 7 (CCL7) antigen, an inflammatory cytokine also known as monocyte chemotactic protein 3 (MCP-3). Human CCL7 is secreted by several tumor cell lines and macrophages as a precursor protein containing 99 amino acids, including an aminoterminal hydrophobic signal sequence. It is one of the most broadly active chemokines, potently inducing chemotaxis of monocytes, basophils, eosinophils, and lymphocytes, as well as degranulation of basophils, eosinophils, and monocytes.
Additional information: Clone REA328 displays negligible binding to Fc receptors.

Alternative names

FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7

Detailed product information

Technical specifications

CloneREA328
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCCL7 (MCP-3)
Alternative names of antigenFIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7
Molecular mass of antigen [kDa]9
Distribution of antigenmacrophages
Entrez Gene ID6354
RRIDAB_2651396, AB_2651397, AB_2651398, AB_2651395

Resources for CCL7 (MCP-3) Antibody, anti-human, REAfinity™

Certificates

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link
to search for Certificates of Analysis (CoA) by lot number.

References for CCL7 (MCP-3) Antibody, anti-human, REAfinity™

Publications

  1. Tsou, C. L. et al. (2007) Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J. Clin. Invest. 117(4): 902-909
  2. Opdenakker, G. et al. (1993) Human monocyte chemotactic protein-3 (MCP-3): molecular cloning of the cDNA and comparison with other chemokines. Biochem. Biophys. Res. Commun. 191(2): 535-542
  3. Menten, P. et al. (2001) Monocyte chemotactic protein-3. Eur. Cytokine Netw. 12(4): 554-560

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