Clone:
REAL582
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
TUBA

Specifications for α Tubulin Antibody, anti-human/mouse/rat, REAdye_lease™

Overview

Clone REAL582 is an antibody fragment derived from the full a Tubulin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL582 recognizes the human, mouse and rat alpha chain of Tubulin (a Tubulin), a heterodimer conisting of homologous but not identical a and b tubulin subunits. Tubulin is a member of the tubulin superfamily, which consists of six members (a, b, g, d, e and z tubulins) Tubulin is expressed by nearly all eukaryotic cells. Cancer cells show moderate to strong cytoplasmic expression, hepatocellular carcinomas have a weakly or negative expression. Tubulin is an essential part of microtubules, which are involved in a variety of cellular processes. They form the cytoskeleton and play a role in mitosis and meiosis.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

TUBA

Detailed product information

Technical specifications

CloneREAL582
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman, mouse, rat
Antigenα Tubulin
Alternative names of antigenTUBA

Resources for α Tubulin Antibody, anti-human/mouse/rat, REAdye_lease™

Certificates

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References for α Tubulin Antibody, anti-human/mouse/rat, REAdye_lease™

Publications

  1. Nogales, E. et al. (1998) Structure of the alpha beta tubulin dimer by electron crystallography. Nature 391(6663): 199-203
  2. Findeisen, P. et al. (2014) Six subgroups and extensive recent duplications characterize the evolution of the eukaryotic tubulin protein family. Genome Biol. Evol. 6(9): 2274-2288

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