Simple exosome isolation and analysis

Simple exosome isolation and analysis

Isolate highly pure exosomes directly from liquid biopsy samples (e.g. blood, urine, or ascites) or cell culture supernatant; or perform a comprehensive exosome analysis, including multiple key markers.

Learn more about our exosome research solutions:

Exosome isolation  
with Exosome Isolation Kits, human

Isolate highly pure exosomes without the need for ultracentrifugation.

• Targeted immunomagnetic isolation based on
CD9, CD63, CD81, or all three makers combined 
• Isolation from cell culture supernatant or liquid biopsy
• Input sample volumes starting from 0.5 mL 
• Fast (<2 h) protocol

Exosome Isolation Kit Pan

MACSPlex Exosome Kit

Exosome analysis 
with MACSPlex Exosome Kit, human

Perform a comprehensive semi-quantitative analysis of several exosome surface proteins in parallel.

• Bead-based flow cytometry assay  
• Analysis of over 30 surface markers
• No pre-enrichment necessary 
• Fast (<2 h) and easy protocol  

Our kits make a difference

Plasma extracellular vesicles (EVs) isolated with our Exosome Isolation Kits* and analyzed with the MACSPlex Exosome Kit reveal strong signals in comparison to EVs isolated by ultracentrifugation.

Surface marker profiles of extracellular vesicles isolated from plasma by ultracentrifugation or immunomagnetic isolation using the Exosome Isolation Kits CD9, CD63, or CD81.
EVs from 2 mL of plasma were isolated using one of the kits or by ultracentrifugation. Amounts were adjusted to a plasma volume of 2 mL, and exosomes were analyzed using the MACSPlex Exosome Kit. Data indicate median APC signal intensities of isolated EVs. REA and mIgG1 indicate isotype control beads.

*Please note: It is not possible to combine the Exosome Isolation Kit Pan, human with the MACSPlex Exosome Kit, human.

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Discover how some of our customers used our exosome research solutions to successfully investigate EVs

Application note

Isolation of highly pure urinary extracellular vesicles suitable for downstream RNA cargo sequencing 
Application note

Robust EV profiling in various sample types with the MACSPlex Exosome Kit
Application note

Combination of Exosome Isolation Kits and MACSPlex Exosome Kit allows phenotyping of EVs released during physical exercise

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