Clone:
REA547
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
gd TCR

Specifications for TCRγ/δ Antibody, anti-rat, REAfinity™

Overview

Clone REA547 recognizes the rat TCRγ/δ antigen. The T cell receptor is a heterodimeric glycoprotein associated with the CD3 antigen. It consists of an α- and a β-chain (TCRα/β) or a γ- and a δ-chain (TCRγ/δ). The γ and δ TCR–chains are composed of constant and variable regions, each encoded by distinct gene segments. The γ-chain forms either disulfide-linked or non-disulfide-linked heterodimers with the δ-subunit. The γ/δ T cell receptor is present on a subset of T lymphocytes in peripheral blood. TCRγ/δ is involved in the antigen recognition of tumor-associated antigens or bacterial antigens presented by MHC class I molecules.
Additional information: Clone REA547 displays negligible binding to Fc receptors.

Alternative names

gd TCR

Detailed product information

Technical specifications

CloneREA547
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesrat
AntigenTCRγ/δ
Alternative names of antigengd TCR
Distribution of antigenT cells
Entrez Gene ID24821, 290108
RRIDAB_2654092, AB_2654093, AB_2654094, AB_2654095, AB_2654096, AB_2654097, AB_2654098, AB_2654099, AB_2654100, AB_2654101, AB_2654102, AB_2654103, AB_2654104, AB_2654091

References for TCRγ/δ Antibody, anti-rat, REAfinity™

Publications

  1. Kühnlein, P. et al. (1994) Identification and characterization of rat gamma/delta T lymphocytes in peripheral lymphoid organs, small intestine, and skin with a monoclonal antibody to a constant determinant of the gamma/delta T cell receptor. J. Immunol. 153(3): 979-986
  2. Chien, Y. H. et al. (1996) Recognition by gamma/delta T cells. Annu. Rev. Immunol. 14: 511-532
  3. Smith-Garvin, J. E. et al. (2009) T cell activation. Annu. Rev. Immunol. 27: 591-619

Related products for
TCRγ/δ Antibody, anti-rat, REAfinity™

2 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?