Clone:
REA967
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
PVRL4, LNIR, PRR4

Specifications for Nectin-4 Antibody, anti-human, REAfinity™

Overview

Clone REA967 recognizes the human nectin-4 protein, also known as the poliovirus receptor-related protein 4 (PVRL4), a type I transmembrane adhesion glycoprotein of the Ig superfamily receptor LNIR. Nectin-4 is specifically expressed in placenta and on breast carcinoma cells. All nectins are known as receptors for the herpes simplex virus.
Additional information: Clone REA967 displays negligible binding to Fc receptors.

Alternative names

PVRL4, LNIR, PRR4

Detailed product information

Technical specifications

CloneREA967
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenNectin-4
Alternative names of antigenPVRL4, LNIR, PRR4
Molecular mass of antigen [kDa]52
Distribution of antigenbreast cancer cells, placenta
Entrez Gene ID81607
RRIDAB_2727313, AB_2727350, AB_2727314, AB_2727351, AB_2727315, AB_2727348, AB_2727312, AB_2727349

References for Nectin-4 Antibody, anti-human, REAfinity™

Publications

  1. Reymond, N. et al. (2001) Nectin4/PRR4, a new afadin-associated member of the nectin family that trans-interacts with nectin1/PRR1 through V domain interaction. J. Biol. Chem. 276(46): 43205-43215
  2. Fabre-Lafay, S. et al. (2005) Nectin-4, a new serological breast cancer marker, is a substrate for tumor necrosis factor-alpha-converting enzyme (TACE)/ADAM-17. J. Biol. Chem. 280(20): 19543-19550
  3. Fabre-Lafay, S. et al. (2007) Nectin-4 is a new histological and serological tumor associated marker for breast cancer. BMC Cancer 7: 73-73

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