Clone:
REA711
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
Mucin-13, DRCC1, RECC

Specifications for MUC-13 Antibody, anti-human, REAfinity™

Overview

Clone REA711 recognizes the human MUC-13 antigen, a 54 kDa transmembrane glycoprotein. MUC-13 may play a role in cell signaling and is involved in barrier function in epithelial tissues. It is highly expressed in epithelial tissues, particularly those of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix, and stomach. Including MUC-13, there are at least five cell surface mucins expressed in the gastrointestinal tract.
Additional information: Clone REA711 displays negligible binding to Fc receptors.

Alternative names

Mucin-13, DRCC1, RECC

Detailed product information

Technical specifications

CloneREA711
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenMUC-13
Alternative names of antigenMucin-13, DRCC1, RECC
Molecular mass of antigen [kDa]53
Distribution of antigenepithelial cells, kidney
Entrez Gene ID56667
RRIDAB_2652970, AB_2652971, AB_2652972, AB_2652973, AB_2652974, AB_2652975, AB_2652976, AB_2652969

References for MUC-13 Antibody, anti-human, REAfinity™

Publications

  1. Williams, S. J. et al. (2001) Muc13, a novel human cell surface mucin expressed by epithelial and hemopoietic cells. J. Biol. Chem. 276(21): 18327-18336
  2. Gupta, B. K. et al. (2012) Increased expression and aberrant localization of mucin 13 in metastatic colon cancer. J. Histochem. Cytochem. 60(11): 822-831
  3. Chauhan, S. C. et al. (2012) MUC13 mucin augments pancreatic tumorigenesis. Mol. Cancer Ther. 11(1): 24-33

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