Type of antibody:
Releasable antibodies, Primary antibodies, Recombinant antibodies
Alternative names:
integrin b5, integrin beta 5, ITGB5

Specifications for Integrin β5 Antibody, anti-human,


Clone REAL463 is an antibody fragment derived from the full Integrin β5 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL463 recognizes the human integrin β5 antigen, a 95 kDa glycoprotein single-pass type I membrane protein. Integrins are a family of transmembrane receptors that mediate adhesion of cells to extracellular matrices, as well as intercellular interactions. These interactions transduce signals that control complex cell functions such as proliferation, differentiation, and survival, and require the regulation of gene expression. Integrins are heterodimeric glycoprotein receptors and exist as non-covalently bound α and β subunits. The integrin αV/β5 heterodimer is found on many types of tissue cells, such as epithelial cells, endothelial cells, keratinocytes, and osteoblastic cells. It is a receptor for fibronectin and vitronectin and acts as a receptor for adenovirus type C.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

integrin b5, integrin beta 5, ITGB5

Detailed product information

Technical specifications

Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable antibodies, Primary antibodies, Recombinant antibodies
AntigenIntegrin β5
Alternative names of antigenintegrin b5, integrin beta 5, ITGB5
Distribution of antigenepithelial cells, endothelial cells, keratinocytes, osteoblasts
RRIDAB_2877052, AB_2877051