Human MCP-1
Alternative names:
CCL2, MCAF

Specifications for Human MCP-1

Overview

MCP-1 stands for monocyte chemotactic protein 1, also termed monocyte chemotactic and activating factor (MCAF) or CCL2. Human MCP-1 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Applications

Human MCP-1 can be used for a variety of applications, including:
  • Chemotactic assays.
  • Inflammation studies.

Alternative names

CCL2, MCAF

Detailed product information

Background information

MCP-1 belongs to the CC chemokine subfamily and is also known as CCL2. It signals predominantly through CCR2. MCP-1 is expressed by various cell types and besides monocyte and tissue macrophages also attracts T cells and NK cells to sites of inflammation. In addition to chemotaxis further pro-inflammatory activities, such as all activation, angiogenesis, and fibrosis are attributed to MCP-1.

Biological activity

  • Chemotaxis of human THP-1 cells
  • research grade: ≥ 1×
    10
    4
    U/mg

Quality description

Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Resources for Human MCP-1

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

Seems like you are coming from USA!
Do you want to visit our website in your country?

Copyright © 2023 Miltenyi Biotec and/or its affiliates. All rights reserved.