Type of antibody:
Primary antibodies
rat IgG2a
Alternative names:
CLEC4N, Clec6a, Clecsf10, Nkcl

Specifications for Dectin-2 Antibody, anti-mouse


Clone KVa7-6E7 specifically recognizes mouse dendritic cell–associated C-type lectin 2 (Dectin-2). Dectin-2 is a type II membrane protein and contains a single carbohydrate recognition domain. Like other C-type lectins, mouse Dectin-2 has conserved motifs for the Ca
-dependent recognition of mannose. Dectin-2 is located in the natural killer gene complex of chromosome 6. Genomic analyses show that beside a full length Dectin-2 transcript two truncated isoforms are produced by alternative splicing, encoding transmembrane proteins of 168–209 amino acids.¹
² The expression of Dectin-2 on mouse monocytes and macrophages can be induced by zymosan and thioglycollate.
Dectin-2 plays a physiological role in antigen presentation and antigen targeting via Dectin-2 can induce a CD8
T cell response.

Alternative names

CLEC4N, Clec6a, Clecsf10, Nkcl

Detailed product information

Technical specifications

Isotyperat IgG2a
Isotype controlIsotype Control Antibody, rat IgG2a
Type of antibodyPrimary antibodies
Alternative names of antigenCLEC4N, Clec6a, Clecsf10, Nkcl
Molecular mass of antigen [kDa]24
Entrez Gene ID56620
RRIDAB_10830717, AB_2889657

Resources for Dectin-2 Antibody, anti-mouse


Please follow this
to search for Certificates of Analysis (CoA) by lot number.

References for Dectin-2 Antibody, anti-mouse


  1. Fernandes, M. J. et al. (1999) Characterization of a novel receptor that maps near the natural killer gene complex: demonstration of carbohydrate binding and expression in hematopoietic cells. Cancer Res. 59: 2709-2717
  2. Taylor, P. R. et al. (2005)
    Dectin-2 is predominantly myeloid restricted and exhibits unique activation-dependent expression on maturing inflammatory monocytes elicited
    in vivo
    Eur. J. Immunol. 35: 2163-2174
  3. Carter, R. W. et al. (2006)
    Induction of CD8
    T cell responses through targeting of antigen to Dectin-2.
    Cell. Immunol. 239: 87-91
  4. Ariizumi, K. et al. (2000) Cloning of a second dendritic cell-associated C-type lectin (dectin-2) and its alternatively spliced isoforms. J. Biol. Chem. 275: 11957-11963

Related products for
Dectin-2 Antibody, anti-mouse

7 products available | view all

Seems like you are coming from USA!
Do you want to visit our website in your country?