Clone:
13G3
Type of antibody:
Primary antibodies
Isotype:
mouse IgG2aκ
Applications:
FC, MICS, IF, IHC
Alternative names:
SLAM family receptor, SLAMF6, SLAM F6, LY108, Lymphocyte antigen 108, SLAM family member 6

Specifications for CD352 (NTB-A) Antibody, anti-mouse

Overview

Clone 13G3 recognizes the mouse CD352 antigen, a single-pass type I membrane protein, also known as SLAM family member 6 (SLAM6) or NK, T, and B cell antigen (NTB-A) belonging to the CD2 subfamily of the immunoglobulin superfamily. It is expressed on NK, T, and B cells. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases. CD352 plays a role in NK cell cytotoxicity and T cell cytokine responses. It controls neutrophil functions and serves as a regulator of both innate and adaptive immune responses.

Alternative names

SLAM family receptor, SLAMF6, SLAM F6, LY108, Lymphocyte antigen 108, SLAM family member 6

Detailed product information

Technical specifications

Clone13G3
Clonalitymonoclonal
Isotypemouse IgG2aκ
Isotype controlIsotype Control Antibody, mouse IgG2a
Hostmouse
Type of antibodyPrimary antibodies
Speciesmouse
AntigenCD352 (NTB-A)
Alternative names of antigenSLAM family receptor, SLAMF6, SLAM F6, LY108, Lymphocyte antigen 108, SLAM family member 6
Molecular mass of antigen [kDa]36
Distribution of antigenB cells, T cells, NK cells
Entrez Gene ID30925
RRIDAB_2657680, AB_2657681, AB_2657682, AB_2657683, AB_2657684, AB_2657685, AB_2657688, AB_2657689

References for CD352 (NTB-A) Antibody, anti-mouse

Publications

  1. Howie, D. et al. (2005) Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions. J. Immunol. 174(10): 5931-5935
  2. Griewank, K. et al. (2007) Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 27(5): 751-762
  3. Peck, S. R. et al. (2000) Ly108: a new member of the mouse CD2 family of cell surface proteins. Immunogenetics 52(1-2): 63-72

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