Clone:
4FR6D3
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC, MICS, IF, IHC
Alternative names:
FGFR-4, FGFR4, TKF, FGF R4

Specifications for CD334 (FGFR4) Antibody, anti-human

Overview

Clone 4FR6D3 recognizes the human CD334 antigen, known as fibroblast growth factor receptor 4 (FGFR4) which is a member of the fibroblast growth factor receptor family. This cell surface tyrosine kinase is a high affinity receptor for both acidic and basic fibroblast growth factor. The binding of CD334 with the acidic fibroblast growth factors FGF2, FGF6, and FGF8, FGF19, and GFG1 induces mitogenesis and differentiation. CD334 is expressed in adrenal, lung, kidney, liver, pancreas, intestine, striated muscle, and spleen tissues of human fetuses. A soluble-form splice variant of FGFR 4 was identified in human gastrointestinal epithelial cells and cancer cells.

Alternative names

FGFR-4, FGFR4, TKF, FGF R4

Detailed product information

Technical specifications

Clone4FR6D3
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD334 (FGFR4)
Alternative names of antigenFGFR-4, FGFR4, TKF, FGF R4
Molecular mass of antigen [kDa]86
Distribution of antigenmyeloid leukemia cells, lung cancer cells, pancreatic carcinoma cells, kidney, liver, lung, spleen
Entrez Gene ID2264
RRIDAB_2657576, AB_2657577, AB_2657578, AB_2657579, AB_2657580, AB_2657581, AB_2657582, AB_2657583, AB_2657584, AB_2657585, AB_2657586, AB_2657587, AB_2657588, AB_2657589

References for CD334 (FGFR4) Antibody, anti-human

Publications

  1. Partanan, J. et al. (1991) FGFR-4, a novel acidic fibroblast growth factor receptor with a distinct expression pattern. EMBO J. 10(6): 1347-1354
  2. Takaishi, S. et al. (2000) Identification of a novel alternative splicing of human FGF receptor 4: soluble-form splice variant expressed in human gastrointestinal epithelial cells. Biochem. Biophys. Res. Commun. 267(2): 658-662
  3. Ron, D. et al. (1993) Fibroblast growth factor receptor 4 is a high affinity receptor for both acidic and basic fibroblast growth factor but not for keratinocyte growth factor. J. Biol. Chem. 268(8): 5388-5394

Related products for
CD334 (FGFR4) Antibody, anti-human

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?