Clone:
REA854
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
JAM-A, JAM-1, F11

Specifications for CD321 (JAM1) Antibody, anti-mouse, REAfinity™

Overview

Clone REA854 recognizes the mouse CD321 antigen, a type I transmembrane glycoprotein containing two extracellular immunoglobulin-like domains. CD321 is a receptor molecule also known as junctional adhesion molecule 1 (JAM1) and is expressed on some epithelial cells, macrophages, and dendritic cells. It is involved in regulating monocyte transmigration as well as in the organization and function of antigen-presenting cells. Furthermore, CD321 acts as a ligand for the integrin LFA1, which plays a role in leukocyte transmigration.
Additional information: Clone REA854 displays negligible binding to Fc receptors.

Alternative names

JAM-A, JAM-1, F11

Detailed product information

Technical specifications

CloneREA854
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD321 (JAM1)
Alternative names of antigenJAM-A, JAM-1, F11
Molecular mass of antigen [kDa]30
Distribution of antigenepithelial cells, macrophages, dendritic cells
Entrez Gene ID16456
RRIDAB_2725838, AB_2725857, AB_2725839, AB_2725858, AB_2725840, AB_2725855, AB_2725837, AB_2725856

References for CD321 (JAM1) Antibody, anti-mouse, REAfinity™

Publications

  1. Malergue, F. et al. (1998) A novel immunoglobulin superfamily junctional molecule expressed by antigen presenting cells, endothelial cells and platelets. Mol. Immunol. 35(17): 1111-1119
  2. Martìn-Padura, I. et al. (1998) Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration. J. Cell Biol. 142(1): 117-127

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CD321 (JAM1) Antibody, anti-mouse, REAfinity™

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