Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
Klrk1, NKG2-D

Specifications for CD267 (TACI) Antibody, anti-mouse, REAfinity™


Clone REA1227 recognizes the mouse CD267 antigen, a type III transmembrane protein receptor that binds to APRIL and BAFF and also interacts with heparan sulfate proteoglycans (HSPGs). Expression of CD267 is found on subset of T cells, marzinal zone (MZ), and B1 B cells. A dual role of TACI has been suggested in regulating B cell activation. TACI
mice have high number of hyper-reactive B cells, indicating an inhibitory role of TACI. On the other hand, mice lacking TACI are unable to mount normal T cell independent type 2 (TI-2) immune response and thus suggesting a positive role in promoting B cell activation.
Additional information: Clone REA1227 displays negligible binding to Fc receptors.

Alternative names

Klrk1, NKG2-D

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
AntigenCD267 (TACI)
Alternative names of antigenKlrk1, NKG2-D
Molecular mass of antigen [kDa]27
Distribution of antigenT cells, B cells
Entrez Gene ID27007
RRIDAB_2811601, AB_2811602, AB_2811603, AB_2811600

Resources for CD267 (TACI) Antibody, anti-mouse, REAfinity™


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References for CD267 (TACI) Antibody, anti-mouse, REAfinity™


  1. Yan, X. et al. (2003) A novel anti-CD146 monoclonal antibody, AA98, inhibits angiogenesis and tumor growth. Blood 102: 184-191
  2. Batten, M. et al. (2004) TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma. J. Immunol. 172: 812-822
  3. Mackay, F. et al. (2008) TACI, an enigmatic BAFF/APRIL receptor, with new unappreciated biochemical and biological properties. Cytokine Growth Factor Rev. 19(3–4): 263-276

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