Specifications for CD159a (NKG2A) Antibody, anti-mouse, REAfinity™
Overview
Clone REA1161 recognizes the CD159a (NKG2A) antigen, an inhibitory natural killer (NK) cell receptor. CD159a forms heterodimer with CD94 and contains a C-type lectin ectodomain. Inhibitory signal is transmitted by the heterodimer via immunoreceptor tyrosine-based inhibitory motifs (ITIMs) and upon ligand engagement, ITIMs are phosphorylated and transmit signal through docking of various tyrosine phosphatases. CD159a/CD94 binds non-classical MHC class I protein, HLA-E. Expression of CD159a is found mainly on NK cells, NKT cells, and on subsets of CD8
+ cells.
Additional information: Clone REA1161 displays negligible binding to Fc receptors.
Alternative names
KLRC1, NKG2ADetailed product information
Technical specifications
| Clone | REA1161 |
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| Clonality | monoclonal |
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| Isotype | recombinant human IgG1 |
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| Isotype control | REA Control Antibody, human IgG1 |
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| Host | human cell line |
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| Type of antibody | Primary antibodies, Recombinant antibodies |
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| Species | mouse |
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| Antigen | CD159a (NKG2A) |
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| Alternative names of antigen | KLRC1, NKG2A |
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| Molecular mass of antigen [kDa] | 28 |
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| Distribution of antigen | NK cells, NKT cells, CD8+ T cells |
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| Entrez Gene ID | 16641 |
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| RRID | AB_2752066, AB_2752063, AB_2752067, AB_2752064, AB_2752068, AB_2752065 |
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