Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
c-kit, KIT, PBT, SCFR

Specifications for CD117 Antibody, anti-human, REAfinity™


Clone REA996 recognizes the human CD117 antigen, also known as c-kit or SCF receptor. CD117 is a 145 kDa receptor tyrosine kinase involved in stem cell signaling, activation, and proliferation. It is expressed on about 1–3% of peripheral blood mononuclear cells (PBMCs) and cord blood cells and on up to 10% of bone marrow cells. CD117 is further expressed on basophils, myeloid dendritic cells, TCRα/β
T cells, CD19
B cells, and CD56
NK cells, as well as on mast cells, melanocytes, and acute myeloid leukemia (AML) blasts.
Additional information: Clone REA996 displays negligible binding to Fc receptor.

Alternative names

c-kit, KIT, PBT, SCFR

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Alternative names of antigenc-kit, KIT, PBT, SCFR
Molecular mass of antigen [kDa]107
Distribution of antigenB cells, endothelial cells, fibroblasts, mast cells, megakaryocytes, NK cells, red blood cells, T cells, stem cells, hematopoietic stem and progenitor cells, leukemia cells, cancer stem cells, basophils, myeloid dendritic cells, bone marrow, brain, kidney
Entrez Gene ID3815
RRIDAB_2727619, AB_2727665, AB_2727620, AB_2727666, AB_2727621, AB_2727667, AB_2727622, AB_2922321, AB_2922315, AB_2922320, AB_2922314, AB_2727664

Resources for CD117 Antibody, anti-human, REAfinity™


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References for CD117 Antibody, anti-human, REAfinity™


  1. Yarden, Y. et al. (1987) Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J. 6(11): 3341-3351
  2. Bühring, H. J. et al. (1991) The product of the proto-oncogene c-kit (P145c-kit) is a human bone marrow surface antigen of hematopoietic precursor cells which is expressed on a subset of acute non-lymphoblastic cells. Leukemia 5: 854-860
  3. Guth, S. et al. (1995) Immunomagnetic isolation and surface phenotyping of human c-kit receptor-expressing cells from peripheral blood. 9th International Congress of Immunology

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