Clone:
REAL915
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
MUC-5AC, MUC5AC, MUC5, Gastric mucin, TBM (Tracheobronchial mucin), major airway glyoprotein, Mucin-5 subtype AC, tracheobronchia

Specifications for Mucin-5AC Antibody, anti-human, REAdye_lease™

Overview

Clone REAL915 is an antibody fragment derived from the full Mucin-5AC antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL915 recognizes the human Mucin-5AC, also known as MUC 5AC, a glycoprotein of gastric and respiratory tract epithelia that protects the mucosa from infection and chemical damage by binding to inhaled microorganisms and particles that are subsequently removed by the mucociliary system. Mucin-5AC is highly expressed in surface mucosal cells of the respiratory tract, stomach epithelia, in Barrett's esophagus epithelium and in the proximal duodenum. It is overexpressed in a number of carcinomas, has been linked to mucus hypersecretion in the respiratory tract and is associated to chronic obstructive pulmonary disease (COPD).
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

MUC-5AC, MUC5AC, MUC5, Gastric mucin, TBM (Tracheobronchial mucin), major airway glyoprotein, Mucin-5 subtype AC, tracheobronchia

Detailed product information

Technical specifications

CloneREAL915
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenMucin-5AC
Alternative names of antigenMUC-5AC, MUC5AC, MUC5, Gastric mucin, TBM (Tracheobronchial mucin), major airway glyoprotein, Mucin-5 subtype AC, tracheobronchia
Distribution of antigenepithelial cells, stomach, esophagus, pancreas, colon

Resources for Mucin-5AC Antibody, anti-human, REAdye_lease™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for Mucin-5AC Antibody, anti-human, REAdye_lease™

Publications

  1. Kocer, B. et al. (2002) Expression of MUC5AC in colorectal carcinoma and relationship with prognosis. Pathol Int. 52(7): 470-477
  2. Terada, T. (2013) An immunohistochemical study of primary signet-ring cell carcinoma of the stomach and colorectum: II. Expression of MUC1, MUC2, MUC5AC, and MUC6 in normal mucosa and in 42 cases. Int J Clin Exp Pathol 6(4): 613-621
  3. Kaur, S. et al. (2017) A Combination of MUC5AC and CA19-9 Improves the Diagnosis of Pancreatic Cancer: A Multicenter Study. Am J Gastroenterol. 112(1): 172-183

Related products for
Mucin-5AC Antibody, anti-human, REAdye_lease™

1 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?