CD83 antibodies, human

CD83 antibodies, human

Clone: REA714 | Dilution: 1:50
Clone REA714 recognizes the human CD83 antigen, a 45 kDa glycoprotein member of the immunoglobulin superfamily of receptors. In humans, CD83 is expressed on the surface of activated dendritic cells (DCs) and can therefore be used as a marker for the phenotypical characterization of DC maturation. CD83 plays a role in antigen presentation and lymphocyte activation.
Additional information: Clone REA714 displays negligible binding to Fc receptors.

Alternative names

B-cell activation protein

Technical specifications

  • Antigen: CD83
  • Clone: REA714
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: B-cell activation protein
  • Entrez Gene ID: 9308
  • Molecular mass of antigen [kDa]: 21
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    , baboon, horse
  • Distribution of antigen: lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, APC-Vio770
  • Selected references

    1. Zhou, L.-J. et al. (1992) A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of J. Immunol. 149: 735-742
    2. Sallusto, F. and Lanzavecchia, A. (1994) Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha. J. Exp. Med. 179: 1109-1118
    3. Zhou, L.-J. and Tedder, T. F. (1995) Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. J. Immunol. 154: 3821-3835
    4. Lechmann, M. et al. (2002) CD83 on dendritic cells: more than just a marker for maturation. Trends Immunol. 23: 273-275
    5. Cao, W. et al. (2005) CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells. Biochem. J. 385: 85-93
Product options: 10
130-110-565

CD83-VioBright FITC, human

for 30
tests
(1)
DKK 1.000,00 
130-110-507

CD83-VioBright FITC, human

for 100
tests
(1)
DKK 2.400,00 
130-110-561

CD83-PE, human

for 30
tests
(1)
DKK 900,00 
130-110-503

CD83-PE, human

for 100
tests
(1)
DKK 2.200,00 
130-110-562

CD83-APC, human

for 30
tests
(1)
DKK 900,00 
130-110-504

CD83-APC, human

for 100
tests
(1)
DKK 2.200,00 
130-110-563

CD83-PE-Vio770, human

for 30
tests
(1)
DKK 1.000,00 
130-110-505

CD83-PE-Vio770, human

for 100
tests
(1)
DKK 2.400,00 
130-110-564

CD83-APC-Vio770, human

for 30
tests
(1)
DKK 1.000,00 
130-110-506

CD83-APC-Vio770, human

for 100
tests
(1)
DKK 2.400,00