CD49e antibodies, mouse and rat

CD49e antibodies, mouse and rat

Clone: HMα5-1 | Dilution: 1:10
Clone HMa5-1 recognizes the mouse and rat CD49e antigen, also known as integrin alpha-5, which is a protein belonging to the integrin alpha chain family. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cellmatrix interaction. Integrin alpha-5 is composed of a heavy and a light chain linked by a disulfide bond. CD49e associates non-covalently with the integrin beta-1 (CD29) forming the very late activation antigen-5 (VLA5) complex. It is expressed on different cell types including thymocytes, mast cells, activated T cells, and splenic B cells.

Alternative names

VLA-5, Integrin alpha-5, ITGA5

Technical specifications

  • Antigen: CD49e
  • Clone: HMα5-1
  • Isotype: hamster IgG
  • Isotype control: For the appropriate isotype control antibody, please refer to the tab Related items.
  • Alternative names of antigen: VLA-5, Integrin alpha-5, ITGA5
  • Entrez Gene ID: 16402
  • Molecular mass of antigen [kDa]: 110
  • Distribution of antigen: thymocytes, mast cells, T cells, B cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Holers, V. M. et al. (1989) Molecular cloning of a murine fibronectin receptor and its expression during inflammation. Expression of VLA-5 is increased in activated peritoneal macrophages in a manner discordant from major histocompatibility complex class II. J. Exp. Med. 169(5): 1589-1605
    2. Hemler, M. E. et al. (1990) LA proteins in the integrin family: structures, functions, and their role on leukocytes. Annu. Rev. Immunol. 8: 365-400
    3. Noto, K. et al. (1995) Identification and functional characterization of mouse CD29 with a mAb. Int. Immunol. 7: 835-842
Product options: 10
130-110-109

CD49e-VioBright FITC, mouse and rat

9 µg in 300 µL (1)
DKK 430,00 
130-110-075

CD49e-VioBright FITC, mouse and rat

30 µg in 1 mL (1)
DKK 850,00 
130-110-106

CD49e-PE, mouse and rat

9 µg in 300 µL (1)
DKK 300,00 
130-110-072

CD49e-PE, mouse and rat

30 µg in 1 mL (1)
DKK 650,00 
130-110-107

CD49e-APC, mouse and rat

9 µg in 300 µL (1)
DKK 430,00 
130-110-073

CD49e-APC, mouse and rat

30 µg in 1 mL (1)
DKK 650,00 
130-110-108

CD49e-PE-Vio770, mouse and rat

9 µg in 300 µL (1)
DKK 530,00 
130-110-074

CD49e-PE-Vio770, mouse and rat

30 µg in 1 mL (1)
DKK 850,00 
130-110-105

CD49e-Biotin, mouse and rat

9 µg in 300 µL (1)
DKK 170,00 
130-110-071

CD49e-Biotin, mouse and rat

30 µg in 1 mL (1)
DKK 350,00