CD314 (NKG2D) antibodies, human

CD314 (NKG2D) antibodies, human

Clone: REA797
Clone REA797 recognizes CD314 (NKG2D), a cell surface receptor of the type II transmembrane receptor NKG2 family. It is expressed on NK cells, CD8
+
α/β T cells, and γ/δ T cells. Though NKG2D itself possesses no intrinsic signaling capability, ligand engagement while associated to the adaptor proteins DAP10 or DAP12 induces cytolytic activation in NK cells as well as costimulation in certain T cell populations. Ligands for NKG2D are stress-inducible MHC class I–related MICA, MICB, and UL16–binding proteins, expressed predominantly on epithelial cells and numerous carcinomas.
Additional information: Clone REA797 displays negligible binding to Fc receptors.

Alternative names

Klrk1, KLR, NKG2D

Technical specifications

  • Antigen: CD314 (NKG2D)
  • Clone: REA797
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Klrk1, KLR, NKG2D
  • Entrez Gene ID: 22914
  • Molecular mass of antigen [kDa]: 25
  • Cross-reactivity:
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    rhesus monkey (
    Macaca mulatta
    )
  • Distribution of antigen: NK cells, T cells
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates:
Product options: 1
130-122-332

CD314 (NKG2D) pure, human

100 µg in 100 µL
DKK 1.455,00