Anti-TCR Vβ7.2 antibodies, human

Anti-TCR Vβ7.2 antibodies, human

Clone: REA677 | Dilution: 1:11
Clone REA677 recognizes the human Vβ7.2 T cell receptor (TCR Vβ7.2). The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. It is suggested that T cells expressing TCRs with Vβ7.2 are protective against a pathogenic immune response in Sjögren's syndrome. TCR Vβ7.2 is expressed on a subset of α/β T cells.
Additional information: Clone REA677 displays negligible binding to Fc receptors.

Alternative names

TCR Vb7.2, TCR Vbeta7.2

Technical specifications

  • Antigen: TCR Vβ7.2
  • Clone: REA677
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: TCR Vb7.2, TCR Vbeta7.2
  • Distribution of antigen: T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Zhao, T. M. et al. (1994) A genetically determined insertion/deletion related polymorphism in human T cell receptor beta chain (TCRB) includes functional variable gene segments. J. Exp. Med. 180(4): 1405-1414
    2. Wei, S. et al. (1994) The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenetics 40(1): 27-36
    3. Manavalan, S. J. et al. (2004) Genomic absence of the gene encoding T cell receptor Vbeta7.2 is linked to the presence of autoantibodies in Sjögren's syndrome. Arthritis Rheum. 50(1): 187-198
Product options: 10
130-110-172

Anti-TCR Vβ7.2-VioBright FITC, human

for 30
tests
(1)
DKK 1.000,00 
130-110-146

Anti-TCR Vβ7.2-VioBright FITC, human

for 100
tests
(1)
DKK 2.400,00 
130-110-169

Anti-TCR Vβ7.2-PE, human

for 30
tests
(1)
DKK 950,00 
130-110-143

Anti-TCR Vβ7.2-PE, human

for 100
tests
(1)
DKK 2.250,00 
130-110-170

Anti-TCR Vβ7.2-APC, human

for 30
tests
(1)
DKK 950,00 
130-110-144

Anti-TCR Vβ7.2-APC, human

for 100
tests
(1)
DKK 2.250,00 
130-110-171

Anti-TCR Vβ7.2-PE-Vio770, human

for 30
tests
(1)
DKK 1.000,00 
130-110-145

Anti-TCR Vβ7.2-PE-Vio770, human

for 100
tests
(1)
DKK 2.400,00 
130-110-168

Anti-TCR Vβ7.2-Biotin, human

for 30
tests
(1)
DKK 800,00 
130-110-142

Anti-TCR Vβ7.2-Biotin, human

for 100
tests
(1)
DKK 1.900,00