CD66e antibodies, human

CD66e antibodies, human

Clone: REA876 | Dilution: 1:50
Clone REA876 recognizes the human CD66e antigen, a member of the immunoglobin superfamily which is also known as carcinoembryonic antigen (CEA) or CEA-related cell adhesion molecules 5 (CEACAM5). CD66e is GPI-linked glycosylated protein found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon. CD66e and other CEACAMs are host receptors for the Dr family of adhesins of
Escherichia coli
. CD66e is an intercellular adhesion molecule and is able to inhibit cellular differentiation. The overexpression of CD66e is used as an indicator for tumor invasiveness.
Additional information: Clone REA876 displays negligible binding to Fc receptors.

Alternative names

CEA, CEACAM5

Technical specifications

  • Antigen: CD66e
  • Clone: REA876
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CEA, CEACAM5
  • Entrez Gene ID: 1048
  • Molecular mass of antigen [kDa]: 71
  • Distribution of antigen: epithelial cells, colon
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Taheri, M. et al. (2000) Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion. J. Biol. Chem. 275(35): 26935-26943
    2. Korotkova, N. et al. (2008)
      Binding of Dr adhesins of
      Escherichia coli
      to carcinoembryonic antigen triggers receptor dissociation.
      Mol. Microbiol. 67(2): 420-434
Product options: 8
for 30
tests
(1)
EUR 80,00 
for 100
tests
(1)
EUR 190,00 
130-114-324

CD66e-PE, human

for 30
tests
(1)
EUR 95,00 
130-114-217

CD66e-PE, human

for 100
tests
(1)
EUR 225,00 
130-114-325

CD66e-APC, human

for 30
tests
(1)
EUR 95,00 
130-114-218

CD66e-APC, human

for 100
tests
(1)
EUR 225,00 
for 30
tests
(1)
EUR 80,00 
for 100
tests
(1)
EUR 190,00 

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