CD62L antibodies, mouse

CD62L antibodies, mouse

Clone: REA828 | Dilution: 1:50
Clone REA828 recognizes mouse CD62L, also known as L-selectin. CD62L is a member of the selectin family of cell adhesion molecules. CD62L is important for the homing of lymphocytes to peripheral lymph nodes through high endothelial venules. It also contributes to leukocyte emigration into acute inflammatory sites. CD62L is a glycoprotein expressed on the cell surface of most thymocytes, T cells, B cells, monocytes, dendritic cells, neutrophils, and eosinophils. It is highly expressed on naive T cells and down-regulated upon differentiation due to activation-dependent shedding. CD62L is also expressed on a subset of CCR7
high
CD44
high
central memory T cells and on CD4
+
CD25
+
regulatory T cells.
Additional information: Clone REA828 displays negligible binding to Fc receptors.

Alternative names

Sell, L-selectin, LECAM-1, Lnhr, Ly-22, Ly-m22, Lyam-1, Lyam1, LAM-1

Technical specifications

  • Antigen: CD62L
  • Clone: REA828
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Sell, L-selectin, LECAM-1, Lnhr, Ly-22, Ly-m22, Lyam-1, Lyam1, LAM-1
  • Entrez Gene ID: 20343
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: B cells, bone marrow, eosinophils, granulocytes, Langerhans cells, lymphocytes, monocytes, neutrophils, NK cells, red blood cells, spleen, T cells, thymocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Siegelman, M. H. et al. (1990) The mouse lymph node homing receptor is identical with the lymphocyte cell surface marker Ly-22: role of the EGF domain in endothelial binding. Cell 61(4): 611-622
    2. Gallatin, W. M. et al. (2006) A cell-surface molecule involved in organ-specific homing of lymphocytes. J. Immunol. 177(1): 5-9
Product options: 18
30 µg in 200 µL (1)
EUR 35,00 
150 µg in 1 mL (1)
EUR 100,00 
130-112-836

CD62L-PE, mouse

30 µg in 200 µL (1)
EUR 65,00 
130-112-647

CD62L-PE, mouse

150 µg in 1 mL (1)
EUR 190,00 
130-112-837

CD62L-APC, mouse

30 µg in 200 µL (1)
EUR 65,00 
130-112-648

CD62L-APC, mouse

150 µg in 1 mL (1)
EUR 190,00 
30 µg in 200 µL (1)
EUR 80,00 
150 µg in 1 mL (1)
EUR 230,00 
30 µg in 200 µL (1)
EUR 85,00 
150 µg in 1 mL (1)
EUR 245,00 
30 µg in 200 µL (1)
EUR 85,00 
150 µg in 1 mL (1)
EUR 245,00 
30 µg in 200 µL (1)
EUR 85,00 
150 µg in 1 mL (1)
EUR 245,00 
30 µg in 200 µL (1)
EUR 85,00 
150 µg in 1 mL (1)
EUR 245,00 
30 µg in 200 µL (1)
EUR 35,00 
150 µg in 1 mL (1)
EUR 100,00 

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