CD58 (LFA-3) antibodies, human

CD58 (LFA-3) antibodies, human

Clone: TS2/9 | Dilution: 1:11
The monoclonal antibody TS2/9 recognizes human CD58, a 45–70 kDa cell surface molecule which is a member of the immunoglobin superfamily. It is expressed on professional antigen-presenting cells (APCs) such as B cells, dendritic cells, macrophages, and epithelial cells as well as on T cells, monocytes, erythrocytes, endothelial cells, and fibroblasts. LFA-3 interacts with CD2 on T cells and is important for interaction between T cells and professional APCs.

Alternative names

LFA-3, ag3

Technical specifications

  • Antigen: CD58 (LFA-3)
  • Clone: TS2/9
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: LFA-3, ag3
  • Distribution of antigen: B cells, dendritic cells, macrophages, T cells, endothelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, Biotin
  • Selected references

    1. Sanchez-Madrid, F. et al. (1982) Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3. Proc. Natl. Acad. Sci. U.S.A. 79: 7489-7493
    2. Dengler, T. J. et al. (1992) Structural and functional epitopes of the human adhesion receptor CD58 (LFA-3). Eur. J. Immunol. 22(11): 2809-2817
    3. Wang, J. H. et al. (1999) Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors. Cell 97(6): 791-803
Product options: 6
for 30
tests
(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 
for 30
tests
(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 
for 30
tests
(1)
EUR 75,00 
for 100
tests
(1)
EUR 185,00 

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