CD48 antibodies – functional grade, mouse

CD48 antibodies – functional grade, mouse

Clone: HM48-1
The HM48-1 antibody reacts with the CD48 mouse antigen, which is a 45 kDa GPI-linked glycoprotein also known as BCM1, blast-1 (human), or OX-45 (rat). CD48 belongs to the SLAM family including CD48, CD244, and CD150. These cell surface receptors were differentially expressed among functionally progenitors. Hematopoietic stem cells are highly purified as CD150
cells, multipotent hematopoietic progenitors are CD244
and most restricted progenitor cells are CD48
. In mouse, the ligands for CD48 are CD2 and CD244.


The mouse CD48 pure – functional grade antibody is suited for functional assays, for example,
in vitro
in vivo
blocking of CD48 binding such as CD48-CD2 interaction and CTL activation.

Alternative names

BCM1, BLAST, Blast-1, MEM-102, SLAMF2, Sgp-60

Technical specifications

  • Antigen: CD48
  • Clone: HM48-1
  • Isotype: hamster IgG1
  • Alternative names of antigen: BCM1, BLAST, Blast-1, MEM-102, SLAMF2, Sgp-60
  • Entrez Gene ID: 12506
  • Molecular mass of antigen [kDa]: 22
  • Distribution of antigen: B cells, granulocytes, leukocytes, lymphocytes, monocytes, red blood cells, T cells
  • Endotoxin level: Endotoxin levels have been tested and do not exceed 0.01 ng/µg of protein.
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
  • Selected references

    1. Latchman, Y. et al. (1998) Cutting edge: Identification of the 2B4 molecule as a counter-receptor for CD48. J. Immunol. 161: 5809-5812
    2. Kato, K. et al. (1992) CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. J. Exp. Med. 176: 1241
    3. Kiel, M.J. et al. (2005) SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell 121(7): 1109-1121
Product options: 1
500 µg in 0.5 mL
EUR 267,00