CD35 antibodies, human

CD35 antibodies, human

Clone: E11 | Dilution: 1:11
The monoclonal antibody E11 recognizes the human cell surface protein CD35, the C3b/C4b receptor, also known as CR1 or complement receptor type I. Four CD35 allotypes with different molecular weights are known; 190, 220, 250, and 280 kDa. CD35 is expressed on hematopoietic cells such as granulocytes, monocytes, B cells, subsets of natural killer (NK) and T cells, erythrocytes, and follicular dendritic cells (DCs). Known functions of CD35 include transport of C3 complexes on erythrocytes, complement activation, phagocytosis, and inhibition of the activation-induced proliferation of T and B cells.

Alternative names

CR1, C3BR, C4BR, KN, C3b/C4b-R

Technical specifications

  • Antigen: CD35
  • Clone: E11
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: CR1, C3BR, C4BR, KN, C3b/C4b-R
  • Entrez Gene ID: 1378
  • Molecular mass of antigen [kDa]: 220
  • Cross-reactivity:
    rhesus monkey (
    Macaca mulatta
    )
    ,
    cynomolgus monkey (
    Macaca fascicularis
    )
    ,
    chimpanzee (
    Pan troglodytes
    )
    ,
    olive baboon (
    Papio anubis
    )
  • Distribution of antigen: dendritic cells, T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, VioBlue, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Reilly, B. et al. (2010)
      Human peripheral CD4
      +
      T-cells expressing complement receptor 1 (CR1, CD35).
      J. Immunol. 184(1 Supplement): 138.3
    2. Reynes, M. et al. (1985) Human follicular dendritic cells express CR1, CR2, and CR3 complement receptor antigens. J. Immunol. 135: 2687-2694
    3. Klickstein, L. B. et al. (1988) Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis. J. Exp. Med. 168: 1699-1717
Product options: 14
130-099-913

CD35-PE, human

for 30
tests
(1)
EUR 90,00 
130-099-922

CD35-PE, human

for 100
tests
(1)
EUR 220,00 
130-099-923

CD35-APC, human

for 30
tests
(1)
EUR 90,00 
130-099-930

CD35-APC, human

for 100
tests
(1)
EUR 220,00 
for 30
tests
(1)
EUR 95,00 
for 100
tests
(1)
EUR 230,00 
for 30
tests
(1)
EUR 100,00 
for 100
tests
(1)
EUR 240,00 
for 30
tests
(1)
EUR 100,00 
for 100
tests
(1)
EUR 240,00 
for 30
tests
(1)
EUR 100,00 
for 100
tests
(1)
EUR 240,00 
for 30
tests
(1)
EUR 75,00 
for 100
tests
(1)
EUR 185,00 

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