CD34 antibodies, mouse

CD34 antibodies, mouse

Clone: REA383 | Dilution: 1:50
Clone REA383 recognizes the mouse CD34 antigen, a highly glycosylated single-pass type I membrane protein also known as mucosialin. CD34 is highly expressed in hematopoietic progenitor cell lines, as well as on endothelial cells, brain, and testis. It is a adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. CD34 acts as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components.
Additional information: Clone REA383 displays negligible binding to Fc receptors.

Alternative names

Mucosialin

Technical specifications

  • Antigen: CD34
  • Clone: REA383
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: Mucosialin
  • Entrez Gene ID: 12490
  • Molecular mass of antigen [kDa]: 37
  • Distribution of antigen: hematopoietic stem cells, endothelial cells, brain, testicle
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC
  • Selected references

    1. Suda, J. et al. (1992) Two types of murine CD34 mRNA generated by alternative splicing. Blood 79(9): 2288-2295
    2. Brown, J. et al. (1991) The gene encoding the stem cell antigen, CD34, is conserved in mouse and expressed in haemopoietic progenitor cell lines, brain, and embryonic fibroblasts. Int. Immunol. 3(2): 175-184
    3. Nakauchi, H. et al. (1999) Further characterization of CD34-low/negative mouse hematopoietic stem cells. Ann. N. Y. Acad. Sci. 872: 57-66
  • Customer reports and application notes

Product options: 1
130-117-775

CD34-FITC, mouse

30 µg in 200 µL (1)
EUR 30,00 

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