CD183 (CXCR3) antibodies, mouse

CD183 (CXCR3) antibodies, mouse

Clone: REA724 | Dilution: 1:50
Clone REA724 recognizes the mouse CD183 antigen, also known as CXCR3, a 40 kDa seven-transmembrane protein belonging to the the G protein–coupled receptor family that mediates the proliferation, survival, and angiogenic activity of mesangial cells through a heterotrimeric G protein signaling pathway. CD183 binds the ligands CXCL9, CXCL10, and CXCL11 and mediates Ca
2+
mobilization and chemotaxis. It is expressed on activated T cells, circulating blood T cells, B cells, and NK cells.
Additional information: Clone REA724 displays negligible binding to Fc receptors.

Alternative names

C-X-C chemokine receptor type 3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor

Technical specifications

  • Antigen: CD183 (CXCR3)
  • Clone: REA724
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: C-X-C chemokine receptor type 3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor
  • Entrez Gene ID: 12766
  • Molecular mass of antigen [kDa]: 41
  • Distribution of antigen: T cells, B cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBright FITC, PE, APC, PE-Vio770
  • Selected references

    1. Tamaru, M. et al. (1998) Cloning of the murine interferon-inducible protein 10 (IP-10) receptor and its specific expression in lymphoid organs. Biochem. Biophys. Res. Commun. 251(1): 41-48
    2. Soto, H. et al. (1998) The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3. Proc. Natl. Acad. Sci. U.S.A. 95(14): 8205-8210
    3. Huttlin, E. L. et al. (2010) A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143(7): 1174-1189
Product options: 8
30 µg in 200 µL (1)
EUR 85,00 
150 µg in 1 mL (1)
EUR 245,00 
30 µg in 200 µL (1)
EUR 65,00 
150 µg in 1 mL (1)
EUR 190,00 
30 µg in 200 µL (1)
EUR 65,00 
150 µg in 1 mL (1)
EUR 190,00 
30 µg in 200 µL (1)
EUR 85,00 
150 µg in 1 mL (1)
EUR 245,00 

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