CD183 (CXCR3) antibodies, mouse

CD183 (CXCR3) antibodies, mouse

Clone: CXCR3-173 | Dilution: 1:10
The monoclonal antibody CXCR3-173 reacts with mouse CD183, also known as CXCR3, which is a 40 kDa seven-transmembrane protein belonging to the G protein-coupled receptor family. CXCR3 binds the ligands CXCL9, CXCL10 and CXCL11 and mediates Ca
2+
mobilization and chemotaxis. It is expressed on activated T cells, circulating blood T cells, B cells and NK cells.

Alternative names

CXCR3, CMKAR3

Technical specifications

  • Antigen: CD183 (CXCR3)
  • Clone: CXCR3-173
  • Isotype: hamster IgG
  • Alternative names of antigen: CXCR3, CMKAR3
  • Entrez Gene ID: 12766
  • Molecular mass of antigen [kDa]: 41
  • Distribution of antigen: B cells, dendritic cells, eosinophils, heart, kidney, liver, NK cells, placenta, plasma cells, skeletal muscle, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: APC, PE
  • Selected references

    1. Loetscher, M. et al. (1996) Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J. Exp. Med. 184(3): 963-969
    2. Qin, S. et al. (1998) The chemokine receptors CXCR3 and CCR5 mark subsets of T cells associated with certain inflammatory reactions. Clin. Invest. 101(4): 746-754
    3. Wells, T. N. et al. (1998) Definition, function and pathophysiological significance of chemokine receptors. Trends Pharmacol. Sci. 19(9): 376-380
Product options: 2
30 µg in 1 mL (1)
EUR 65,00 
30 µg in 1 mL (1)
EUR 65,00