CD182 (CXCR2) antibodies, human

CD182 (CXCR2) antibodies, human

Clone: REA208 | Dilution: 1:11
Clone REA208 recognizes CD182 (CXCR2), which belongs to the class of chemokine receptors specific for CXC chemokines. Chemokine receptors are G-coupled protein receptors (GPCR) with seven-transmembrane domains and consist of an α-subunit and a βγ-complex. In humans, interleukin 8 (IL-8) is one of most potent chemokine which binds to CXCR2. Expression of CD182 is found on several cell types including leukocytes, endothelial, and epithelial cells. CD182 plays a critical role in neutrophil homeostatis, angiogenesis, and in pathological conditions such as acute lung injury, lung diseases, and asthma.
Additional information: Clone REA208 displays negligible binding to Fc receptors.

Alternative names

CXCR2, CDw128b, CMKAR2, IL8R2, IL8RA, CD128b, IL-8RB

Technical specifications

  • Antigen: CD182 (CXCR2)
  • Clone: REA208
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CXCR2, CDw128b, CMKAR2, IL8R2, IL8RA, CD128b, IL-8RB
  • Distribution of antigen: leukocytes, endothelial cells, epithelial cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Belperio, J. A. et al. (2005) CXCR2/CXCR2 ligand biology during lung transplant ischemia-reperfusion injury. J. Immunol. 175: 6931-6939
    2. Thatcher, T. H. et al. (2005) Role of CXCR2 in cigarette smoke-induced lung inflammation. Am. J. Physiol. Lung Cell Mol. Physiol. 289: L322-L328
Product options: 8
for 30
tests
(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 
for 30
tests
(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 
for 30
tests
(1)
EUR 100,00 
for 100
tests
(1)
EUR 240,00 
for 30
tests
(1)
EUR 75,00 
for 100
tests
(1)
EUR 185,00