CD158f (KIR2DL5) antibodies, human

CD158f (KIR2DL5) antibodies, human

Clone: REA955 | Dilution: 1:50
Clone REA955 recognizes the human CD158f (KIR2DL5) antigen, a member of the killer immunoglobulin-like receptor (KIR) family, which recognizes subsets of HLA alleles. Expression is found mainly on CD56
dim
CD16
+
natural killer (NK) cells but also on a subset of CD8
+
T cells. KIRs are monomeric receptors possessing high allelic polymorphism, with either two or three Ig-like extracellular domains.
Additional information: Clone REA955 displays negligible binding to Fc receptors.

Alternative names

KIR2DL5A, KIR2DL5B

Technical specifications

  • Antigen: CD158f
  • Clone: REA955
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: KIR2DL5A, KIR2DL5B
  • Entrez Gene ID: 57292
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio615, PE-Vio770, Biotin
  • Selected references

    1. Gomez-Lozano, N. et al. (2002) Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B. Immunogenetics 54(5): 314-319
    2. Estefania, E. et al. (2007) Human KIR2DL5 is an inhibitory receptor expressed on the surface of NK and T lymphocyte subsets. J. Immunol. 178(7): 4402-4410
    3. Gomez-Lozano, N. et al. (2007) Epigenetic silencing of potentially functional KIR2DL5 alleles: Implications for the acquisition of KIR repertoires by NK cells. Eur. J. Immunol. 37(7): 1954-1965
Product options: 10
for 30
tests
(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 
for 30
tests
(1)
EUR 90,00 
for 100
tests
(1)
EUR 220,00 
for 30
tests
(1)
EUR 100,00 
for 100
tests
(1)
EUR 240,00 
for 30
tests
(1)
EUR 100,00 
for 100
tests
(1)
EUR 240,00 
for 30
tests
(1)
EUR 75,00 
for 100
tests
(1)
EUR 185,00