CD137 antibodies, mouse

CD137 antibodies, mouse

Clone: REA936 | Dilution: 1:50
Clone REA936 recognizes the mouse CD137 antigen, a single-pass type I membrane protein also known as 4-1BB or TNFRSF9, which is a member of the TNFR superfamily. CD137 is expressed on the cell surface of T cells upon activation. The interaction of CD137 with its ligand, 4-1BBL, on antigen-presenting cells delivers a bidirectional co-stimulatory signal. CD137 engagement is shown to be required for CD8
+
T cell survival and memory formation. CD137 is reported to have a strong antagonistic effect in
in vitro
functional assays.
Additional information: Clone REA936 displays negligible binding to Fc receptors.

Alternative names

TNFRSF9, 4-1BB, CDw137, ILA, Ly63

Technical specifications

  • Antigen: CD137
  • Clone: REA936
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: TNFRSF9, 4-1BB, CDw137, ILA, Ly63
  • Entrez Gene ID: 21942
  • Molecular mass of antigen [kDa]: 25
  • Distribution of antigen: B cells, epithelial cells, fibroblasts, dendritic cells, lymphocytes, macrophages, monocytes, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE-Vio615, PE-Vio770, APC-Vio770, Biotin, PE, APC
  • Selected references

    1. Pollok, K. E. et al. (1993) Inducible T cell antigen 4-1BB. Analysis of expression and function. J. Immunol. 150(3): 771-781
    2. Tan, J. T. et al. (2000) Analysis of expression and function of the costimulatory molecule 4-1BB in alloimmune responses. Transplantation 70(1): 175-183
Product options: 9
130-115-566

CD137-PE, mouse

30 µg in 200 µL (1)
EUR 65,00 
130-115-451

CD137-PE, mouse

150 µg in 1 mL (1)
EUR 190,00 
130-115-567

CD137-APC, mouse

30 µg in 200 µL (1)
EUR 65,00 
30 µg in 200 µL (1)
EUR 85,00 
150 µg in 1 mL (1)
EUR 245,00 
30 µg in 200 µL (1)
EUR 85,00 
30 µg in 200 µL (1)
EUR 85,00 
30 µg in 200 µL (1)
EUR 35,00 
150 µg in 1 mL (1)
EUR 100,00