CD11c antibodies, human

CD11c antibodies, human

Clone: REA618
Clone REA618 recognizes the human CD11c antigen, a 145–150 kDa type I transmembrane glycoprotein, which is also known as integrin αX or CR4. It is expressed on monocytes, macrophages, NK cells, granulocytes, myeloid dendritic cells (MDCs), and subsets of T and B cells. On myeloid dendritic cells, CD11c is highly expressed on type 1 myeloid dendritic cells (CD1c (BDCA-1)
MDC1s) and low on type 2 myeloid dendritic cells (CD1c (BDCA-1)
MDC2s). CD11c, also known as integrin integrin αX or CR4, has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.
Additional information: Clone REA618 displays negligible binding to Fc receptors.

Alternative names

95, CR4, integrin αX, ITGAX, p150

Technical specifications

  • Antigen: CD11c
  • Clone: REA618
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: 95, CR4, integrin αX, ITGAX, p150
  • Entrez Gene ID: 3687
  • Molecular mass of antigen [kDa]: 126
  • Distribution of antigen: B cells, dendritic cells, granulocytes, leukemia cells, lymphocytes, macrophages, monocytes, myeloid cells, NK cells, T cells
  • Product format: Antibodies are supplied in phosphate-buffered saline (PBS), pH 7.2. The product contains no preservative and is sterile filtered. Always handle under aseptic conditions.
  • Fixation: The antibody is suited for staining of formaldehyde-fixed cells.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: pure
Product options: 1
100 µg in 100 µL
EUR 148,00