Anti-IL-17RC antibodies, human

Anti-IL-17RC antibodies, human

Clone: REA571 | Dilution: 1:11
Clone REA571 recognizes the human IL-17RC antigen, a single-pass transmembrane protein belonging to the IL-17 cytokine family. The IL-17 receptor (IL-17R) subfamily includes IL-17RA, IL-17RB, IL-17RC, IL-17RD, and IL-17RE that induce signaling via recruitment of signaling intermediates. Together with IL-17RA IL-17RC is able to form a receptor complex capable specific for IL-17A and IL-17F. IL-17RC is expressed in prostate and prostate cancer, skeletal muscle, kidney, and placenta.
Additional information: Clone REA571 displays negligible binding to Fc receptors.

Alternative names

CANDF9, IL17-RL

Technical specifications

  • Antigen: IL-17RC
  • Clone: REA571
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: CANDF9, IL17-RL
  • Entrez Gene ID: 84818
  • Molecular mass of antigen [kDa]: 84
  • Distribution of antigen: prostate cancer cells, skeletal muscle, kidney, placenta
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, Biotin
  • Selected references

    1. Haudenschild, D. et al. (2002) Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer. J. Biol. Chem. 277(6): 4309-4316
    2. Toy, D. et al. (2006) Cutting edge: interleukin 17 signals through a heteromeric receptor complex. J. Immunol. 177(1): 36-39
    3. Kuestner, R. E. et al. (2007) Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F. J. Immunol. 179(8): 5462-5473
    4. Ho, A. W. et al. (2010) IL-17RC: a partner in IL-17 signaling and beyond. Semin. Immunol. 32(1): 33-42
Product options: 8
for 30
tests
(1)
EUR 80,00 
for 100
tests
(1)
EUR 190,00 
for 30
tests
(1)
EUR 95,00 
for 100
tests
(1)
EUR 225,00 
for 30
tests
(1)
EUR 95,00 
for 100
tests
(1)
EUR 225,00 
for 30
tests
(1)
EUR 80,00 
for 100
tests
(1)
EUR 190,00 

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