Anti-HLA-A9 antibodies, human

Anti-HLA-A9 antibodies, human

Clone: REA127 | Dilution: 1:11
Clone REA127 recognizes HLA A9, a class I human leukocyte antigen (HLA). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of 3 domains, of which one comprises the peptide binding groove. Antigens binding to class I molecules are 8–10 amino acids long and play an important role in recognition of the virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells.
Additional information: Clone REA127 displays negligible binding to Fc receptors.

Alternative names

HLA-A

Technical specifications

  • Antigen: HLA-A9
  • Clone: REA127
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: HLA-A
  • Entrez Gene ID: 3105
  • Molecular mass of antigen [kDa]: 38
  • Distribution of antigen: B cells, dendritic cells, endothelial cells, macrophages, granulocytes, T cells, NK cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Hewitt, E. W. et al. (2003) The MHC class I antigen presentation pathway: strategies for viral immune evasion. Immunology 110(2): 163-169
Product options: 10
for 30
tests
(1)
EUR 80,00 
for 100
tests
(1)
EUR 190,00 
for 30
tests
(1)
EUR 95,00 
for 100
tests
(1)
EUR 225,00 
for 30
tests
(1)
EUR 95,00 
for 100
tests
(1)
EUR 225,00 
for 30
tests
(1)
EUR 100,00 
for 100
tests
(1)
EUR 240,00 
for 30
tests
(1)
EUR 80,00 
for 100
tests
(1)
EUR 190,00 

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