Anti-iNKT MicroBeads, human

Anti-iNKT MicroBeads, human

Anti-iNKT MicroBeads have been developed for the positive selection of human invariant natural killer T cells (iNKT cells) based on the expression of the TCR α-chain Vα24-Jα18.

Background information

iNKT cells represent a distinct lymphocyte population, characterized by expression of an invariant T cell receptor α-chain and certain TCR β-chains (Vα24-Jα18 combined with Vβ11). iNKT cells are involved in immunoregulatory processes such as tolerance, host defense, and tumor surveillance.
Due to the nature of the antibody, a limited degree of pre-activation of target cells might occur after separation with this product.

Columns

MS, LS, XS, or autoMACS
®
Columns.
  • Selected references

    1. Exley, M. et al. (2008) Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR α-chain CDR3 loop. Eur. J. Immunol. 38: 1756-1766
    2. Montoya, J. C. et al. (2007) Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology 122: 1-14
  • Brochures and posters

Product options: 1
for 2×
10
9
total cells
EUR 510,00 

Related products

2 products available