TLR7/8/9 Antagonists can be used to inhibit TLR7/8/9 mediated cellular responses, such as activation of immune cells, human PBMCs, murine splenocytes or isolated immune cells (e.g., B cells and pDCs).
TLR7/8/9 Antagonists can be used to inhibit signaling in TLR7/8/9-
expressing recombinant cell lines.
ODN 2088 is a widely used inhibitory ODN inhibiting TLR7, TLR8 and TLR91,2,4-7
. ODN 2088 forms tertiary structures (G tetrads).