CD162 antibodies, human

CD162 antibodies, human

Clone: REA319 | Dilution: 1:50
Clone REA319 recognizes the human CD162 antigen, a single-pass type I membrane protein which is also known as P-selectin glycoprotein ligand 1 (PSGL-1). CD162 is expressed on neutrophils, monocytes, and most lymphocytes. It is the high affinity receptor for CD62P (P-selectin) on myeloid cells and stimulated T lymphocytes and mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. CD162 is also involved in homeostasis including stem cell homing to the thymus and mature T cell homing to secondary lymphoid organs. It has been found to bind the homeostatic chemokines CCL19 and CCL21 and to support the chemotactic response to these chemokines.
Additional information: Clone REA319 displays negligible binding to Fc receptors.

Alternative names


Technical specifications

  • Antigen: CD162
  • Clone: REA319
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: PSGL-1, SELPLG
  • Entrez Gene ID: 9332
  • Molecular mass of antigen [kDa]: 121
  • Distribution of antigen: neutrophils, monocytes, lymphocytes
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: VioBlue
  • Selected references

    1. Frenette, P. S. et al. (2000)
      P-selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions
      in vivo
      J. Exp. Med. 191(8): 1413-1422
    2. Sako, D. et al. (1993) Expression cloning of a functional glycoprotein ligand for P-selectin. Cell 75(6): 1179-1186
    3. Carlow, D. A. et al. (2009) PSGL-1 function in immunity and steady state homeostasis. Immunol. Rev. 230(1): 75-96
    4. Evani, S.J. et al. (2016)
      Biophysical regulation of
      Chlamydia pneumoniae
      -infected monocyte recruitment to atherosclerotic foci.
      Sci. Rep. 6
Product options: 2
for 30
CNY 1,615.00
for 100
CNY 3,910.00

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