Clone:
REA1083
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
TNFSF8, CD30LG, CD30L

Specifications for CD153 Antibody, anti-mouse, REAfinity™

Overview

Clone REA1083 recognizes the mouse CD153 (CD30 ligand) antigen, a 40 kDa type II membrane protein belonging to the NGF/TNF superfamily. It is expressed by activated CD4
+
and CD8
+
T cells. The interaction between CD30 and CD153 enhance the proliferation of stimulated T cells but in the presence of the REA1083 antibody this effect is blocked.
In vivo
treatment with this antibody is reported to inhibit or delay immune reactions.
Additional information: Clone REA1083 displays negligible binding to Fc receptors.

Alternative names

TNFSF8, CD30LG, CD30L

Detailed product information

Technical specifications

CloneREA1083
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD153
Alternative names of antigenTNFSF8, CD30LG, CD30L
Molecular mass of antigen [kDa]27
Distribution of antigenB cells, granulocytes, macrophages, monocytes, T cells, CD4+ T cells, CD8+ T cells, bone marrow
Entrez Gene ID21949
RRIDAB_2733388, AB_2733340, AB_2732958, AB_2732959, AB_2734002, AB_2734003, AB_2733502, AB_2733503, AB_2733768

Resources for CD153 Antibody, anti-mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD153 Antibody, anti-mouse, REAfinity™

Publications

  1. al-Shamkhani, A. et al. (1996) OX40 is differentially expressed on activated rat and mouse T cells and is the sole receptor for the OX40 ligand. Eur. J. Immunol. 26(8): 1695-1699
  2. Akiba, H. et al. (1999) CD28-independent costimulation of T cells by OX40 ligand and CD70 on activated B cells. J. Immunol. 162(12): 7058-7066
  3. Kjaergaard, J. et al. (2001) Augmentation versus inhibition: effects of conjunctional OX-40 receptor monoclonal antibody and IL-2 treatment on adoptive immunotherapy of advanced tumor. J. Immunol. 167: 6669-6677

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