CD83 antibodies, mouse

CD83 antibodies, mouse

Clone: REA304 | Dilution: 1:10
Clone REA304 recognizes the mouse CD83 antigen, a Single-pass type I membrane protein which belongs to the immunoglobulin superfamily. Murine CD83 is moderately expressed on resting T cells and DC, but strongly increases in its expression on T cells following activation with antigenic peptides or T cell receptor-specific monoclonal antibody. When returning to the resting state, T cells down-regulate CD83 again. Histological analysis of serial spleen sections revealed a CD83 expression pattern resembling that of MIDC-8, a known murine DC marker molecule.
Additional information: Clone REA304 displays negligible binding to Fc receptors.

Alternative names

B-cell activation protein, Cell surface protein HB15

Technical specifications

  • Antigen: CD83
  • Clone: REA304
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: B-cell activation protein, Cell surface protein HB15
  • Entrez Gene ID: 12522
  • Molecular mass of antigen [kDa]: 19
  • Distribution of antigen: T cells, dendritic cells, spleen
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, Biotin
  • Selected references

    1. Lüthje, K. et al. (2008) CD83 regulates splenic B cell maturation and peripheral B cell homeostasis. Int. Immunol. 20(8): 949-960
    2. Twist, C. J. et al. (1998) The mouse CD83 gene: structure, domain organization, and chromosome localization. Immunogenetics 48(6): 383-393
    3. Wolenski, M. et al. (2003) Expression of CD83 in the murine immune system. Med. Microbiol. Immun. 192(4): 189-192
Product options: 12
130-104-522

CD83-FITC, mouse

9 µg in 300 µL (1)
CHF  33.00
130-104-473

CD83-FITC, mouse

30 µg in 1 mL (1)
CHF  45.00
130-104-523

CD83-PE, mouse

9 µg in 300 µL (1)
CHF  42.00
130-104-474

CD83-PE, mouse

30 µg in 1 mL (1)
CHF  85.00
130-104-524

CD83-APC, mouse

9 µg in 300 µL (1)
CHF  65.00
130-104-475

CD83-APC, mouse

30 µg in 1 mL (1)
CHF  85.00
9 µg in 300 µL (1)
CHF  75.00
30 µg in 1 mL (1)
CHF  110.00
9 µg in 300 µL (1)
CHF  75.00
30 µg in 1 mL (1)
CHF  110.00
9 µg in 300 µL (1)
CHF  28.00
30 µg in 1 mL (1)
CHF  45.00

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