CD51/CD61 antibodies, human

CD51/CD61 antibodies, human

Clone: 23C6 | Dilution: 1:11
The monoclonal antibody 23C6 recognizes the human heterodimeric complex CD51/CD61, also known as integrin αv/β3. The dimers are expressed on melanoma cells, endothelial cells, on osteoclasts, and in a very low density on platelets. The CD51/CD61 complex mediates adhesion to fibronectin, fibrinogen, vitronectin, thrombospondin, osteopontin, and collagen.

Alternative names

ITGAV, MSK8, VNRA, VTNR, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, ITGB3

Technical specifications

  • Antigen: CD51/CD61
  • Clone: 23C6
  • Isotype: mouse IgG1κ
  • Isotype control: Mouse IgG1 – isotype control antibodies
  • Alternative names of antigen: ITGAV, MSK8, VNRA, VTNR, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, ITGB3
  • Entrez Gene ID: 3685, 3690
  • Molecular mass of antigen [kDa]: 197
  • Cross-reactivity: rabbit, chicken
  • Distribution of antigen: endothelial cells, osteoclasts
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, PE-Vio770, APC-Vio770, PerCP-Vio700, Biotin
  • Selected references

    1. Chuntharapai, A. et al. (1993) Blocking monoclonal antibodies to alpha V beta 3 integrin: a unique epitope of alpha V beta 3 integrin is present on human osteoclasts. Exp. Cell Res. 205(2): 345-352
    2. Athanasou, N. A. et al. (1990) New sites of cellular vitronectin receptor immunoreactivity detected with osteoclast-reacting monoclonal antibodies 13C2 and 23C6. Bone Miner. 8(1): 7-22
Product options: 14
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for 100
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CHF  290.00
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CHF  120.00
for 100
tests
(1)
CHF  290.00
for 30
tests
(1)
CHF  130.00
for 100
tests
(1)
CHF  315.00
for 30
tests
(1)
CHF  130.00
for 100
tests
(1)
CHF  315.00
for 30
tests
(1)
CHF  130.00
for 100
tests
(1)
CHF  315.00
for 30
tests
(1)
CHF  100.00
for 100
tests
(1)
CHF  245.00

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