CD45RA antibodies, human

CD45RA antibodies, human

Clone: REA1047 | Dilution: 1:50
Clone REA1047 recognizes the human CD45RA antigen which is expressed on naive CD4
+
and CD8
+
T cells as well as on CD8
+
effector T cells. CD45RA is also present on subsets of B and NK cells as well as on plasmacytoid dendritic cells. The CD45RA antibody recognizes the 220 kDa isoform of the leukocyte common antigen (LCA), a transmembrane tyrosine phosphatase.
Additional information: Clone REA1047 displays negligible binding to Fc receptors.

Alternative names

Ptprc, B220, CD45, CD45R, GP180, L-CA, Ly-5, T200

Technical specifications

  • Antigen: CD45RA
  • Clone: REA1047
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control (S) antibodies
  • Alternative names of antigen: Ptprc, B220, CD45, CD45R, GP180, L-CA, Ly-5, T200
  • Entrez Gene ID: 5788
  • Molecular mass of antigen [kDa]: 145
  • Cross-reactivity:
    chimpanzee (
    Pan troglodytes
    )
  • Distribution of antigen: B cells, monocytes, NK cells, T cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: FITC, PE, APC, VioBlue, VioGreen, PE-Vio615, PE-Vio770, APC-Vio770, PerCP-Vio700, VioBright 515, Biotin
  • Selected references

    1. Cantisan, S. et al. (2010)
      CD45RA expression on HCMV-specific effector memory CD8
      +
      T cells is associated with the duration and intensity of HCMV replication after transplantation.
      Clin. Immunol. 137(1): 81-88
    2. Braun, T. et al. (2012)
      Effector CD4
      +
      CD45RA
      CD25
      bright
      Foxp3
      bright
      regulatory T cell (eTreg) distribution is significantly impaired in chronic myelomonocytic leukemia (CMML) and correlates with TET 2 mutational status.
      Blood 120: 2808-2808
Product options: 22
for 30
tests
(1)
CHF  84.00
for 100
tests
(1)
CHF  200.00
130-117-852

CD45RA-PE, human

for 30
tests
(1)
CHF  110.00
130-117-741

CD45RA-PE, human

for 100
tests
(1)
CHF  268.00
for 30
tests
(1)
CHF  110.00
for 100
tests
(1)
CHF  268.00
for 30
tests
(1)
CHF  131.00
for 100
tests
(1)
CHF  320.00
for 30
tests
(1)
CHF  131.00
for 100
tests
(1)
CHF  320.00
for 30
tests
(1)
CHF  137.00
for 100
tests
(1)
CHF  331.00
for 30
tests
(1)
CHF  137.00
for 100
tests
(1)
CHF  331.00
for 30
tests
(1)
CHF  137.00
for 100
tests
(1)
CHF  331.00
for 30
tests
(1)
CHF  137.00
for 100
tests
(1)
CHF  331.00
for 30
tests
(1)
CHF  173.00
for 100
tests
(1)
CHF  415.00
for 30
tests
(1)
CHF  84.00
for 100
tests
(1)
CHF  200.00

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