CD150 (SLAM) antibodies, mouse

CD150 (SLAM) antibodies, mouse

Clone: REA299 | Dilution: 1:10
Clone REA299 recognizes the mouse CD150 antigen, a 75-95 kD single-pass type I membrane protein also known as signaling lymphocyte activation molecule (SLAM). CD150 belongs to the immunoglobulin superfamily and acts as a self ligand. Expression of CD150 is found on B cells, dendritic cells and activated/memory T cells. It is involved in functions such as stimulation, proliferation and inhibition of apoptosis of B cells, stimulation and IFN-γ production in Th1 T-cell clones and recently it has been identified as the second receptor for measles virus. In combination with CD48 and CD244, CD150 is a useful marker for hematopoietic stem cell studies.
Additional information: Clone REA299 displays negligible binding to Fc receptors.

Alternative names

SLAMF1, CDw150, ESTM51, IPO-3, SLAM

Technical specifications

  • Antigen: CD150 (SLAM)
  • Clone: REA299
  • Isotype: recombinant human IgG1
  • Isotype control: REA Control antibodies
  • Alternative names of antigen: SLAMF1, CDw150, ESTM51, IPO-3, SLAM
  • Entrez Gene ID: 27218
  • Molecular mass of antigen [kDa]: 35
  • Distribution of antigen: B cells, dendritic cells, T cells, hematopoietic stem cells
  • Product format: Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
  • Fixation: Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
  • Storage: Store protected from light at 2–8 °C. Do not freeze.
  • Available conjugates: PE, APC, PE-Vio770, Biotin
  • Selected references

    1. Bleharski, J. R. et al. (2001) Signaling lymphocytic activation molecule is expressed on CD40 ligand-activated dendritic cells and directly augments production of inflammatory cytokines. J. Immunol. 167(6): 3167-3181
    2. Castro, A. G. et al. (1999) Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): differential expression and responsiveness in Tʜ1 and Tʜ2 cells. J. Immunol. 163(11): 5860-5870
    3. Wang, N. et al. (2004) The cell surface receptor SLAM controls T cell and macrophage functions. J. Immunol. 199(9): 1255-1264
  • Customer reports and application notes

Product options: 8
9 µg in 300 µL (1)
CHF  42.00
30 µg in 1 mL (1)
CHF  85.00
9 µg in 300 µL (1)
CHF  65.00
30 µg in 1 mL (1)
CHF  85.00
9 µg in 300 µL (1)
CHF  75.00
30 µg in 1 mL (1)
CHF  110.00
9 µg in 300 µL (1)
CHF  28.00
30 µg in 1 mL (1)
CHF  45.00

Related products

2 products available